PNC-27

PNC‑27 — Research Use Only

PNC‑27 is a synthetic anticancer peptide derived from the p53-MDM2 binding domain. It is referenced in scientific literature for experimental research in tumor cell apoptosis, membrane-targeted cancer studies, and peptide–membrane interaction analyses. This peptide is supplied exclusively for laboratory research applications, including in vitro experiments and analytical investigations.

Manufactured to high purity standards, PNC‑27 is intended strictly for non-clinical research use by qualified personnel.

Product Specifications

Peptide Name: PNC‑27

Synonyms: PNC27, PNC‑27 anti-cancer peptide

CAS Number: 1159861‑00‑3

Peptide Sequence:
H‑Pro‑Pro‑Leu‑Ser‑Gln‑Glu‑Thr‑Phe‑Ser‑Asp‑Leu‑Trp‑Lys‑Leu‑Leu‑Lys‑Lys‑Trp‑Lys‑Met‑Arg‑Arg‑Asn‑Gln‑Phe‑Trp‑Val‑Lys‑Val‑Gln‑Arg‑Gly‑OH

Molecular Formula: C₁₈₈H₂₉₃N₅₃O₄₄S

Molecular Weight: ~4031.7 Da

Form: Lyophilized powder

Purity: ≥ 99% (HPLC verified; batch-specific COA available)

Solubility: Soluble in sterile water or appropriate laboratory buffers

Analytical documentation and batch certificates are available upon request for research verification.

Intended Research Applications

✔ In vitro cancer cell apoptosis studies
✔ Membrane-targeted anticancer peptide research
✔ Peptide–receptor and peptide–membrane interaction studies
✔ Investigations of p53/HDM2 signaling pathways

Applications listed are for informational purposes only and do not imply approved or intended medical, therapeutic, or diagnostic use.

Storage & Handling

Store at ≤ −20 °C for long-term stability

Protect from moisture, heat, and direct light

Handle using appropriate laboratory PPE

Reconstitute and dispose of material according to institutional laboratory protocols

Regulatory & Safety Disclaimer

FOR RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

This product is sold strictly as a research chemical. It is not intended for human use, therapeutic use, diagnostic use, or veterinary use. This compound has not been evaluated, approved, or licensed by Health Canada, the FDA, or any other regulatory authority.

The purchaser acknowledges that this product will be handled only by qualified personnel in a laboratory setting and assumes full responsibility for compliance with all applicable Canadian laws, regulations, and institutional guidelines.